Smoking damages the genes in minutes



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US study: Tobacco smoke toxins spread within minutes in the body. Smoking can damage genes after a cigarette.

US scientists have found that the first puff of a cigarette can damage genes. The toxic ingredients of tobacco smoke develop their harmful effects within minutes, according to the US researchers, referring to their current test results.

In addition to the already known negative immediate effects of smoke such as irritated eyes, dry mouth and nose mucosa, poorly perfused, dull-looking skin and a deterioration in the sense of taste, the US scientists have now in their study a direct effect of polycyclic aromatic hydrocarbons (PAH) detected. Within minutes of smoking a cigarette, PAHs have an effect on the body, which can lead to cancer-promoting genetic changes, Stephen S. Hecht from the University of Minnesota and colleagues report on the results of their study in the current issue of the journal "Research in Chemical Toxicology ”.

PAHs have a harmful effect within minutes As part of their research, the US researchers added additional, labeled PAHs to normal cigarettes in order to be able to track the path of the toxins in the body of twelve volunteer test subjects. Her study showed that it only took 15 to 30 minutes after smoking until the PAHs in the blood turn into a substance that could cause genetic changes and cancer. The first draft of a cigarette is harmful and potentially carcinogenic, say the researchers from the University of Minnesota in Minneapolis. According to Stephen S. Hecht, tobacco smoke PAHs are associated with lung tumors and at least 18 other cancers, with lung cancer alone killing around 3,000 people worldwide. The experts assume that 90 percent of lung cancer, 73 percent of chronic obstructive pulmonary disease and 65 percent of floor cancers, as well as a third of all coronary heart disease, can be attributed to smoking.

Genetic Changes Already After the First Cigarette The harmful effects of cigarettes that occurred within minutes would amount to a direct injection into the bloodstream, the US scientists continue. The study leader Stephen S. Hecht emphasized that the deadly PAHs reached their highest efficiency after only 15 to 30 minutes. The U.S. scientists therefore warned against believing that smoking could be stopped in time for the onset of a serious illness. Because the genetic damage could possibly occur after the first cigarette, according to the US researchers. The results of the study should therefore be a clear warning to all people, the scientists concluded. Hecht and colleagues also referred to the uniqueness of their current investigation. It was a novelty, because thanks to the direct examination method, the effects of smoking on human metabolism could be tracked for the first time without having to take other factors such as air pollution and nutrition into account, emphasized Stephen S. Hecht.

Tobacco smoke pollutants: Multiple health hazards The study by the US scientists focuses on the core problem of tobacco smoking, because the pollutant intake during smoking is enormous. Experts assume that if you consume one box (20 cigarettes) a day over a period of 20 years, your lungs will absorb a total of six kilograms of smoke dust and one cup of tar ("condensate") each year. This would reduce the life expectancy of smokers by an average of six years. In addition, the nicotine causes circulatory disorders and the carbon monoxide deficiency in all organs. Furthermore, tobacco smoking is considered a risk factor for a variety of different forms of cancer, including cancer of the throat, larynx, esophagus, lung, stomach, kidney or pancreas. In addition, asthma, chronic obstructive pulmonary diseases (COPD, "smoker's cough"), pulmonary emphysema, chronic bronchitis and other lung diseases are also favored by smoking, as are erectile dysfunction, strokes, coronary heart diseases and heart attacks. In addition, the risk of peripheral arterial disease ("smoker's leg"), other vascular diseases, liver cirrhosis, gastrointestinal ulcers, chronic gum loss (periodontitis), weakened immune systems, premature aging of the skin and delayed wound healing are also directly related to tobacco smoking. According to experts, age-related macular degeneration (the most common cause of blindness in Europe) and irreversible impairments of brain performance can also result from cigarette consumption.

According to the US scientists, the fact that not every smoker automatically falls ill within minutes of the negative effects of PAHs can be attributed to the body's self-healing powers, which depending on the smoker can work well or less well. However, the risk of illness is already there after the first cigarette, according to Stephen S. Hecht and colleagues. (fp)

Also read:
Special form of lung cancer in smokers
Pistachios as protection against lung cancer
Lung cancer can be sniffed out
Diagnosis smoker's lung: disease rate increases
Smoking damages the genes in minutes

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Comments:

  1. Onfroi

    Damn it! Cool! You answered yourself. The meaning of life and everything else. Resolved, no kidding.

  2. Arion

    Agree, it is a remarkable piece

  3. Jerron

    the most valuable message

  4. Gere

    As a nice message

  5. Sekani

    There is something in this. Thank you for the information, now I will not make such a mistake.



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